Immunoglobulin E (IgE) is a class of antibody (immune protein) associated with allergic reactions. It is normally found in very small amounts in the blood. This test measures the amount of allergen-specific IgE in the blood in order to detect an allergy to a particular substance. IgE is an antibody that functions as part of the body’s immune system, its defense against “intruders.” When someone with a predisposition to allergies is exposed to a potential allergen such as food, grass, or animal dander for the first time, that person becomes sensitized. The person’s body perceives the potential allergen as a foreign substance and produces a specific IgE antibody that binds to specialized mast cells in the skin, respiratory system, and gastrointestinal tract, and to basophils (a type of white blood cell) in the bloodstream. With the next exposure, these attached IgE antibodies recognize the allergen and cause the mast and basophil cells to release histamine and other chemicals, resulting in an allergic reaction that begins at the exposure site.
Immunoglobulin E (IgE) is an antibody that is produced by the body’s immune system in response to a perceived threat. It is one of five classes of immunoglobulins (A, G, M, D, and E) and is normally present in the blood in very small amounts. This test measures the amount of IgE in the blood and may be used to screen for and detect allergic diseases. Immunoglobulin E is associated with allergic responses including asthma and to a lesser degree with immunity to parasites.
Sample: Blood (serum)
Reference: Less than 100 IU/ml
Frequency: Twice week
Please refer to ‘Allergy screening’ (Allergie scr. – Microbiology). There are specific tests to verify the presence of antibodies for inhaled and food allergies.
Common Lab Tests
At MLS we carry out a vast number of tests every day, but there are some that are requested more frequently. If you want to browse our list of most common lab tests, click on the link below.
All MLS Lab Tests
Our analysts and laboratory scientists conduct tests in hematology, microbiology, infection serology, special chemistry, and many more areas. For a complete list of the tests we carry out, click on the link below.